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Rethinking the National Clinical Research Continuum

Recorded: December 8, 2021

The ecosystem of evidence generation is rapidly changing. The available data that could be used to inform clinical research is becoming more decentralized and the need for more diverse participation is being encouraged. As research entities, pharmaceutical companies, and health systems seek to adapt to this shift, they also face significant obstacles at all phases of clinical research such as cost, regulation, ability to recruit diverse patients, and access to the right clinical trial resources. This panel will discuss our speakers' experiences and actions that could be done today to reduce this friction to enable clinical trials to accelerate the discovery and development of innovative therapeutics by harnessing the power of everyday healthcare.

  • Learn about the value of data sharing between institutes and health providers, learning networks, and how streamlining resources could take the burden off each individual research entity and democratize research opportunities available through primary care physicians.
  • Discuss how researchers can diversify trial participant representation, no matter the trial site location or patient socioeconomic status, to include the historically understudied and reduce disparity in resulting therapies.
  • Understand the research benefit of real-world evidence sourced from de-identified clinical data, its impact on the speed of trials from study to market and through post-study evaluation, and how real-world evidence is being encouraged through national policy.

Engage with us to help us rethink the historic evidence generation model and how to leverage data and technology to advance new medicine and therapies so patients get the treatment they need, and doctors get the information they need to deliver better care.


Martin Mendoza, PhD, Director of Health Equity, All of Us Research Program, National Institutes of Health

Gideon Scott Gordon, PhD, Senior Health Informatics Officer, Office of Strategic Programs, Center for Drug Evaluation and Research, U.S. Food and Drug Administration

Gillian Bartlett-Esquilant, PhD, Associate Dean for Population Health & Outcomes Research, Co-Director of the Translational Biosciences PhD and Professor of Family & Community Medicine, University of Missouri

David Hedges, PhD MS, Lead Data Scientist, Billings Clinic

Joseph Kliegman, PhD, Research Strategy Executive, Cerner (moderator)