Research Question: What is the association between previous or pre-existing cardiovascular conditions and COVID-19 severity in pediatric patients?
Research Findings: In this cohort study of 171,416 US individuals aged 2 months to 17 years with SARS-CoV- 2 (COVID-19) infection, cardiac arrest, cardiogenic shock, heart surgery, cardiopulmonary disease, heart failure, hypotension, nontraumatic cerebral hemorrhage, pericarditis, or biventricular defects were associated with increased COVID-19 severity.
Research Meaning: The findings suggest that some previous or preexisting cardiovascular conditions are associated with increased severity of COVID-19 among pediatric patients in the US and that morbidity may be increased among individuals children younger than 12 years with previous cardiac arrest.